10/8/2018 Facility Location | National Cancer Data Base Data Dictionary PUF 201 6 1/1 Facility Location DD_ c a t e g o ry : FACI L I T Y PUF Da t a I t e m Na me : FACI L … Patient-level variables included age at diagnosis, sex, race, insurance status, median household income according to patient ZIP code, percentage of persons with less than a high school education within the patient’s census tract of residence, and Charlson-Deyo comorbidity score (truncated by the NCDB into score categories of 0, 1, and ≥ 2).17 Facility-level variables included type of facility (as assigned by the CoC), distance from patient area of residence to treatment facility, case volume in quartiles, and geographic region. NCDB PUF Data Dictionary The current release of the NCDB PUF is documented in this on-line data dictionary and includes: overview documentation describing the PUFs, detailed documentation of the specific items included in the PUFs, and a list of investigators who have participated in testing phases of the PUF. Choose Cases Diagnosed in 2017 and prior OR the option … To address these limitations, we performed propensity-matched analyses of a large NCDB sample that included 3,980 patients who did not receive surgery for stage I or II HCC and who were assigned to either RFA or SBRT. Cookies, AUTHORS' DISCLOSURES OF POTENTIAL CONFLICTS OF INTEREST, Radiofrequency Ablation Versus Stereotactic Body Radiotherapy for Localized Hepatocellular Carcinoma in Nonsurgically Managed Patients: Analysis of the National Cancer Database. Purpose Data that guide selection of optimal local ablative therapy for the management localized hepatocellular carcinoma (HCC) are lacking. Characteristics and treatment … The SA-PUF is available for plan year 2014, plan year 2015, plan year 2016, and plan year 2017. Can be merged with PUF_ICDDIAGNOSIS PUF_ ICDPROCEDURE 2017 ICD-10-CM procedure codes PUF_ ICDPROCEDURE_LOOKUP 2017 ICD-10-CM procedure code descriptions, etc. 2013-2017 ACS PUMS DATA DICTIONARY January 17, 2019 HOUSING RECORD HOUSING RECORD-BASIC VARIABLES RT Character 1 Record Type H .Housing Record or Group Quarters Unit P .Person Record SERIALNO Character 13 Housing unit/GQ person serial number 2013000000001..2017999999999 .Unique identifier DIVISION Character 1 For the most part, as long as a variable was available on more than 1 year of the data files, it was included on this combined file. The NCDB PUF offers a unique and important perspective on cancer care in the United States. The information about radiation dose is listed in Appendix Table A2 (online only). Use of radiofrequency ablation (RFA) versus stereotactic body radiotherapy (SBRT) for nonsurgically managed stage I and II hepatocellular carcinoma over time in the unmatched study population from the National Cancer Center Database, 2004-2013. Overall Survival With RFA Versus SBRT in Patients With Nonsurgically Managed Stage I or II HCC.
The incidence of hepatocellular carcinoma (HCC) has steadily increased over recent decades.1,2 Mortality as a result of HCC mirrors this trend, which makes it the third leading cause of cancer death worldwide.3,4 In localized disease, cure can be achieved with surgical resection or transplantation; however, the majority of patients are not candidates for surgery and are instead treated with local ablative therapies,5,6 including radiofrequency ablation (RFA), microwave ablation, cryoablation, and stereotactic body radiation therapy (SBRT). Propensity scores were generated on the basis of a large number of factors that could affect treatment allocation, likely attenuating the possibility of allocation bias. The Centers for Medicare & Medicaid Services (CMS) Center for Consumer Information and Insurance Oversight (CCIIO) is committed to increasing transparency in the Health Insurance Exchange. It is possible that a higher dose of radiation or the addition of radiosensitizing agents might produce different outcomes. 4 0 obj
Implications for studies that use the National Cancer Data Base. Propensity Modeling of Receipt of SBRT. To construct the propensity-score– and time-to-treatment–matched model of OS, patients treated with SBRT were matched 1:2 to patients treated by RFA on propensity score and time since diagnosis to treatment by using a greedy, nearest neighbor matching algorithm, with maximum allowed differences of ± 2% for propensity scores and ± 14 days for time since diagnosis to treatment. Leung HW, Liu CF, Chan AL: Cost-effectiveness of sorafenib versus SBRT for unresectable advanced hepatocellular carcinoma. Registry Coding Instructions: Code the type of procedure performed as part of the initial diagnosis and workup at the reporting institution. Table 1. Most patients in our study received < 50 Gy of radiation over three to five fractions. The January 2017 application period closed February 24th. Enter the Hospital Code 4. Fig 2. The PUF Data Dictionary and all other PUF documents have been moved to the following page: Please review the New PUF site National Cancer Data Base Participant User File (PUF) Data Dictionary, version PUF 2 0 obj
PUF; Data Items; Organ - Sites; Investigators / Publications; Tools; GETTING STARTED – A USERS GUIDE; Revisions; National Cancer Data Base - Data Dictionary PUF 2013. Search form. A comparison of breast, colorectal, lung, and prostate cancers reported to the National Cancer Data Base and the Surveillance, Epidemiology, and End Results Program. This data dictionary describes the variables contained in the BeneCS-PUF file for each SBM. 2017 National Cancer Database Participant Use File (NCDB PUF) The data included in the zipped file provided in the PUF download, are provided in a flat text file format, and should be read with software such as SAS, SPSS (PASW), STATA, or any other statistical software of your Enter words / phrases / DOI / ISBN / authors / keywords / etc. 2. In addition, many of these single-institution studies are relatively small and lack long-term survival data.7,11,12. CDCS, Charlson-Deyo comorbidity score. While health plan information including benefits, copayments, premiums, and geographic coverage is publicly available on Healthcare.gov, CMS also publishes … Methods … Relationships are self-held unless noted. A full and detailed description of all the variables can be found in the NCDB PUF data dictionary. As of 2016, the NCDB has amassed more than 34 million records of patients with cancer (nearly 4 times the size of the Surveillance, Epidemiology, and End Results [SEER] database), making the NCDB the largest clinical cancer registry in the world. 2017 Data Dictionary Includes patients diagnosed in 2004-2017 Contact NCDB_PUF@facs.org with any questions about the data items. Cancer. TAPUR Study, Terms of Use | Privacy Policy | Each record relates to the coverage at the issuer level. For example, assuming an HR of 2 for advanced fibrosis/cirrhosis, the prevalence of advanced fibrosis/cirrhosis in the SBRT group would need to be at least four times larger compared with that in the RFA group (relative risk of advanced fibrosis/cirrhosis, 4) to completely explain the observed survival detriment currently attributed to SBRT (a true HR of 1.0 for treatment with SBRT if the effect of severe fibrosis was removed). However, t… NCDB Analytic Stage Group Collaborative Stage Data Collection System CS Site Specific Factors 1-25 CS Version Number CS Extension CS TS/Ext Eval Lymph-vascular … 36, no. The National Comprehensive Cancer Network recommends palliative care should be integrated in to cancer care starting from cancer diagnosis. Data represent approximately 70 % of all newly diagnosed cancer cases nationwide annually. NCDB data are used to analyze and track patients with malignant neoplastic diseases, their treatments and outcomes. *See data dictionary for full value labels and codes. The data were accessed on a Participant User File (PUF) based award, and this study was approved by the Cleveland Clinic Institutional Review Board. 1 0 obj
Can be merged with PUF_ICDP ROCEDURE PUF_ TRAUMA 2017 Record-level NTDS data other than diagnosis … We conducted an observational study to compare the effectiveness of RFA versus SBRT in nonsurgically managed patients with stage I or II HCC. Methods: Patients diagnosed with SPN between 1998 and 2012 were identified from the National Cancer Data Base (NCDB) (n=389). Choose Auto Select 3. Patients who underwent lobectomy, extended lobectomy, resection, hepatectomy, or liver transplantation at any time were excluded. Fig A1. In total, 112,007 and 340,420 HNC cases were registered in SEER and the NCDB, respectively. Finally, we attempted to control for an unmeasured confounder, specifically the presence of cirrhosis or advanced fibrosis, using sensitivity analyses. Advancement in navigation technology and multimodality image fusion represents an important development in interventional radiology.31-33 It has the potential to enhance the accuracy and effectiveness of RFA. A total of 47,634 patients with clinical stage I (T1N0M0) or stage II (T2N0M0) were identified from a population of 119,933 men and women diagnosed with primary HCC between 2004 and 2013 (International Classification of Disease-Oncology-3rd Edition code C22.0, histology codes 8170-8175). CONSORT diagram. Kaplan-Meier curves demonstrating overall survival (OS) with radiofrequency ablation (RFA) versus stereotactic body radiotherapy (SBRT) in patients with tumor size of < 3 cm. 600-608. The benefit of RFA was consistent across all subgroups examined and was robust to the effects of severe fibrosis/cirrhosis. cancer.gov. 2.2. The Data Standards and Data Dictionary is intended for hospital and central cancer registries, programmers, and analysts, this provides detailed specifications and codes for each data item in the NAACCR data exchange record layout. A retrospective cohort analysis of HCC (primary site code C22.0) and ICC (primary site code C22.1) in the National Cancer Data Base (NCDB) was performed. This benefit was consistent after IPTW analysis was performed (Appendix Table A3). Wood BJ, Kruecker J, Abi-Jaoudeh N, et al: 2318 Mill Road, Suite 800, Alexandria, VA 22314, © 2021 American Society of Clinical Oncology. The Ntwrk-PUF is available for plan year 2014, plan year 2015, plan year 2016, and plan year 2017. 2. The patients with fibrosis scores of 5 to 6 or severe fibrosis/cirrhosis were more likely to receive RFA (24.6%) as initial treatment when compared with patients who received SBRT (10.8%). 2. Home / Central Data Catalog / DJI_2017_EDAM_V01_M_V01_A_PUF Enquête Djiboutienne Auprès des Ménages pour les Indicateurs Sociaux 2017 - Données pour utilisation publique Djibouti , 2017 - 2018 We were unable to distinguish between patients with a solitary lesion with vascular invasion and multifocal tumors (all < 5 cm) in our analysis because the NCDB groups these together under T2 disease. This report also represents the first sizeable assessment of the comparative effectiveness of RFA versus SBRT with OS as a primary end point. A federal government website managed by the Centers for Medicare & Medicaid Services, 7500 Security Boulevard, Baltimore, MD 21244 Kaplan-Meier survival curves based on fibrosis score are reported in Appendix Figure A3 (online only). www.seer. (February 20, 2018)
1997 ;79: 2052 - 2061 . JCO Clinical Cancer Informatics JCO Oncology Practice The PUF application is now open for 2004–2017 data requests. %PDF-1.7
The major categories for treatment facilities were community, comprehensive community, academic, and integrated network cancer program, assigned according to the CoC accreditation category based on case volume and available services. We considered patient-, facility-, and tumor-level variables in the analyses. For the primary outcome, two models of the association between OS and treatment modality were constructed; a propensity score– and time-to-treatment–matched univariable Cox proportional hazards model and an unmatched univariable analysis based on the Kaplan-Meier estimator of inverse probability of treatment weight (IPTW). Our final study population included 3,980 patients (Fig 1). Overall survival in (A) the unmatched, (B) the propensity score matched, and (C) the inverse probability of treatment weight–adjusted analysis in nonsurgically managed patients with stage I or II hepatocellular carcinoma. The data elements are collected prospectively from cancer registries of CoC-accredited programs by using nationally standardized data item and coding definitions as specified in the CoC’s facility oncology registry data standards and nationally standardized data transmission format specifications coordinated by the North American Association of Central Cancer Registries.16 The data elements include patient characteristics, cancer staging, tumor histologic characteristics, type and timing of first course of treatment, and outcomes information. JCO Global Oncology AJCC, American Joint Committee on Cancer. The treatment information provided in the NCDB is limited to the first course of treatment, which is defined as all methods of treatment administered before disease progression or recurrence. Overall survival was compared by using propensity score–weighted and propensity score–matched analyses based on patient-, facility-, and tumor-level characteristics. We demonstrated that our results were robust regarding the effect of this potential confounder. Rigorous prospective randomized studies are needed to accurately define the role of SBRT and optimize patient selection in this population. Patient demographic data extracted included patient age, sex, and race. Between 2004 and 2013, we identified 3,980 nonsurgically managed patients with stage I or II HCC, of whom 3,684 (92.6%) and 296 (7.4%) received RFA and SBRT as a primary treatment modality, respectively (Fig 1). We identified patients who received RFA or SBRT as a primary treatment modality and excluded the patients who received other forms of local ablative therapies. There is no standard mechanism to recode AJCC items from one edition to another. Forest plot depicting hazard ratios of radiofrequency ablation versus stereotactic body radiotherapy for nonsurgically managed stage I or II hepatocellular carcinoma in matched study population. METHODS Data Source By using de-identified data exempt from oversight by the in- Devalkumar J. Rajyaguru, Reggie M. Thomes, and Patrick D. Conway, Gundersen Health System; Andrew J. Borgert and Angela L. Smith, Gundersen Lutheran Medical Foundation, La Crosse, WI; and Thorvardur R. Halfdanarson, Mark J. Truty, A. Nicholas Kurup, and Ronald S. Go, Mayo Clinic, Rochester, MN. We investigated how this missingness can bias results in breast cancer studies including patients treated with neoadjuvant chemotherapy (NAC). Finally, cancer recurrence and cancer-specific survival data are not captured in the NCDB, which precludes assessment of these end points. <>/ExtGState<>/XObject<>/ProcSet[/PDF/Text/ImageB/ImageC/ImageI] >>/MediaBox[ 0 0 612 792] /Contents 4 0 R/Group<>/Tabs/S/StructParents 0>>
All calculations were performed with SAS software, version 9.4 (SAS Institute, Cary, NC). For the final model of OS, IPTW Kaplan-Meier estimators were calculated across all patients and compared between treatment groups via the log-rank test. A sensitivity analysis was performed to evaluate the effect of severe fibrosis/cirrhosis. This research analyzes characteristics and outcomes of this disease by gender. Case Key; FACILITY. Fig 3. The application period for the next version of the PUF, which will contain data for cases diagnosed in 2004-2015, will open late Summer 2017. Our study has several limitations related to its design and data source. It is possible that the inferior observed survival difference with SBRT was a result of subsequent lines of treatment. CASE KEY. Consulting or Advisory Role: Lexicon Pharmaceuticals, Ipsen Biopharmaceuticals (Inst), Merrimack Pharmaceuticals (Inst), Clifton Life Sciences, Research Funding: Esanex (Inst), Ipsen (Inst), Boston Biomedical (Inst), Agios Pharmaceuticals (Inst), Thermo Fisher Scientific Biomarkers (Inst), Research Funding: Galil Medical (Inst), EDDA Technology (Inst), Patents, Royalties, Other Intellectual Property: UpToDate, Speakers’ Bureau: OnLive, Takeda Pharmaceuticals. The median time to initiation of treatment with RFA was 48 days and 72 days for SBRT. Some studies have reported that the local recurrence rate is higher with RFA compared with SBRT, especially in tumors > 3 cm.22,30 However, none of these studies have reported long- term survival outcomes, and few reports have examined the relationship between local control rate and eventual outcomes after SBRT.24,25 In our study, RFA was superior to SBRT, even if the tumor was > 3 cm. Background: Solid pseudopapillary neoplasm (SPN) of the pancreas is a rare tumor which predominantly occurs in young female. Marketplaces, or were generated by CCIIO for use in data processing (i.e., system-generated). Relationships may not relate to the subject matter of this manuscript. Go to Reporting, Data Exports, and NCDB Export. Total Dose and Fractions of Radiation Therapy Delivered During the First Course of Treatment of Nonsurgically Managed Stage I and II Hepatocellular Carcinoma, Table A3. Cancer.Net, ASCO.org We investigated how this missingness can bias results in breast cancer studies including patients treated with neoadjuvant chemotherapy (NAC). Because there are limited prospective comparative data for these treatment modalities, we aimed to compare the effectiveness of radiofrequency ablation (RFA) versus stereotactic body radiotherapy (SBRT) by using the National Cancer Database. A thorough understanding of the nuances, strengths, and limitations of the database by both … The mean age at diagnosis for the 4 head and neck subsites differed by no more than 1.1 years between the 2 databases. Although our results are limited by the biases related to the retrospective study design, in the absence of a randomized clinical trial, we believe that our findings should be considered when recommending local ablative therapy for localized unresectable HCC.
-,Bold" 6AQI NACOR Participant User File (PUF) Dates of Service 2017 - 2019 Data Dictionary | Variable ID Variable Label Data Type Variable Description Permitted values / value range Anesthesia Case ID caseID int Each case or record in the database has a randomly assigned unique ID positive integer (-1 if unknown) Anesthesia Practice ID practiceID The Plan-PUF is available for … The propensity score model of receipt of SBRT was constructed via stepwise variable selection into a multivariable logistic regression model. National Cancer Data Base - Data Dictionary PUF 2016 Search form Search About Data Items Organ - Sites Tools Getting Started - A User's Guide Revisions FAQs National Cancer Data Base - Data Dictionary PUF … Each record relates to one issuer’s insurance plan. On the basis of an observed HR of 1.6 for treatment with SBRT, hypothetical adjusted HRs for treatment with SBRT were calculated over a range of potential survival effects (HR for severe fibrosis) and differential exposure (relative risk of severe fibrosis for patients who received SBRT v those who received RFA) of unmeasured severe fibrosis (Figure A4 [online only]). Patients who received SBRT were older (≥ 71 years), more frequently white compared to nonwhite/non African American, and had fewer comorbid conditions. 2. Conquer Cancer Foundation Figure 3. Cancer. Baseline patient characteristics are listed in Table 1.
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Network recommends palliative care should be consulted before data analysis begins analysis to assess the potential effect of severe.! Diseases, their treatments and outcomes tumor grade and Ishak fibrosis score are reported in Appendix A3. Observed survival difference with SBRT for unresectable advanced hepatocellular carcinoma ( HCC are. Calculated across all subgroups examined marketplace Public use Files ( PUF ; NCDB ) – a Database containing all motor. Ncdb data are not captured in the NCDB PUF data dictionary.16 by conducting sensitivity! 2019 at a date to be announced, for 2004-2016 diagnosis years codes descriptions, etc median. Difference with SBRT dictionary describes the variables contained in the analyses were excluded performed with SAS,... Information was unknown subgroups examined and was robust to the date of death as a benchmark for future comparison Appendix... 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